Understanding and enhancing the distinction between self and non/altered self

Dissecting and rewiring (multi)cellular circuits to uncover and develop immune-based/like mechanisms for disease treatment and prevention

The immune system has a remarkable ability to distinguish between healthy (self) and unhealthy (non/altered self) cells and eliminate only the latter. This process can depend on a single cell or millions of cells that transmit information to one another.

Using and developing genetic and genomic tools we aim to augment, redirect, and generate new types of immune responses to eliminate and reprogram “altered self” cells, including cancer, senescent, virally infected, and other types of dysfunctional disease driving cells.

How? By decoding and integrating mechanisms that have evolved for millions of years and are imprinted in immune and non-immune cells with mechanisms that we “evolve” and rationally design in the lab through synthetic biology and directed evolution.

Livnat Jerby
Assistant Professor

Jeehyun Yoe, Ph.D. Postdoctoral Fellow

Jeehyun Yoe, Ph.D.
Postdoctoral Fellow

Reece Villarin Akana PhD Student, Cancer Biology

Reece Villarin Akana
PhD Student, Cancer Biology

Young-Min Kim, Ph.D.
Postdoctoral Fellow

Dixian Zhu, Ph.D.
Postdoctoral Fellow

Olivia Laveroni Research Assistant

Olivia Laveroni
Research Assistant

Chang Sun, Ph.D.
Postdoctoral Fellow

Mike Tsai
PhD student, Cancer Biology

Yuxin Cai, Ph.D.
Postdoctoral Fellow

Christine Yiwen Yeh MD/ PhD Student, BMI; co-advisor Sylvia Plevritis

Christine Yiwen Yeh
MD/ PhD Student, BMI; co-advised by Sylvia Plevritis

Kristen Frombach
PhD student, Cancer Biology

Celeste Zesati Diaz
PhD student, Cancer Biology; co-advised by Jennifer Cochran

Karmen Aguirre
PhD Student, Cancer Biology

Soua Lee
Administrative Associate

Contact

Department of Genetics
Stanford University
Biomedical Innovation Building (BMI)
240 Pasteur Dr, Palo Alto, CA 94304
Office phone: (650) 497-0294

 

Open positions

Job openings are available for outstanding researchers, graduate students, and future postdocs, who are highly motivated and have relevant research experience. To apply email your CV and a brief synopsis of your research experience and interests.